This study evaluates the Social Return on Investment (SROI) of implementing measures to prevent fragility fractures in postmenopausal women with osteoporosis (OP) in Spain. Stakeholders agreed on four main actions: establishing fracture liaison services (FLSs), harmonizing clinical practice guidelines and training healthcare professionals (HCPs), promoting HCPs’ adherence to fracture registries, and raising public awareness of OP and fragility fractures. The study concludes that implementing actions to improve secondary fracture prevention would result in substantial social benefits, significantly outweighing the investment when considering direct, indirect, and intangible costs.