Atopic dermatitis (AD) is a chronic, inflammatory skin disease affecting all age groups, but particularly children. This systematic review provides an overview of the humanistic and economic disease burden in the paediatric population with AD in Spain.
The evidence, collected from 11 observational studies published in the last 10 years, presented most common patient characteristics, disease burden, patient-reported outcomes, resource utilisation, and treatment patterns.
The burden of AD extends beyond physical symptoms, with associated comorbidities such as asthma and impaired health-related quality of life and mental health disorders, particularly in severe cases. Traditional treatments, primarily topical corticosteroids, face adherence and efficacy challenges.
Despite promising innovative treatments and available biological therapies, their use is still limited in paediatric population. The findings of the present review highlight the scarce scientific evidence on the economic burden of paediatric AD, as well as the most updated humanistic evidence of the disease.
At the same time, the need for tailored care and innovative therapeutic interventions to address the multifaceted challenges of paediatric AD in Spain is evident.