Unmet Needs in the Management of Chronic Kidney Disease-Associated Pruritus and the Characteristics of the Ideal Treatment: A Spanish Cross-Sectional Survey from a Multidisciplinary Perspective
Chronic kidney disease-associated pruritus (CKD-aP) is underdiagnosed and not fully understood by healthcare professionals, which leads to poor patient management and impacts patients’ quality of life (QoL). The aim was to analyse unmet needs in CKD-aP management and explore the attributes/characteristics that the ideal CKD-aP treatment should have from the perspective of a group of […]
Cost‑Effectiveness Analysis of Abrocitinib Compared with Dupilumab for Adolescents With Severe Atopic Dermatitis in Spain
Severe atopic dermatitis in adolescents represents a significant burden in quality of life and healthcare resource use, within a context of expanding systemic treatment options. This analysis shows that abrocitinib may provide a more efficient alternative compared to dupilumab, delivering improved health outcomes alongside lower costs from the Spanish NHS perspective. Findings support value optimisation […]
Characteristics of patients with neurofibromatosis and patient and caregiver perspectives on the impact of the disease and its clinical management in Spain and Portugal
Neurofibromatosis results in a significant multidimensional burden on quality of life, with clear impact on both patients and caregivers in Spain and Portugal, particularly in pain, clinical complications and psychosocial domains. Despite therapeutic progress, limitations in satisfaction and care coordination remain, alongside unmet psychological support needs. This context reinforces the need for more integrated, outcomes-driven […]
Clinical characteristics and management of Spanish adults patients with phenylketonuria
To describe the sociodemographic and clinical characteristics and management of patients with phenylketonuria (PKU) followed in centres, services, and reference units (CSUR) or clinical excellence units specialised in inborn errors of metabolism (IEM). Additionally, to determine patients’ health-related quality of life (HRQoL).
Growth and gastrointestinal tolerance of healthy formula-fed infants: A multicentre, prospective observational study
Infant formula with human milk oligosaccharides (HMOs) and increased β-palmitate mimics breast milk nutritional composition and clinical benefits. We aimed to assess formula-fed infant growth, gastrointestinal tolerance, infections, and parental satisfaction with a partly fermented infant formula with an improved lipid profile (enriched with β-palmitate and docosahexaenoic/arachidonic acid) and short and long-chain oligosaccharides (scGOS/lcFOS [9:1]) […]
Aspectos nutricionales de los pacientes con parálisis cerebral: un estudio observacional y multicéntrico en España
Multicentric observational study. The goal of the study was to describe the clinical and nutritional characteristics of Spanish children with CP. Our study shows that Spanish children with CP, especially those with greater severe motor impairment, are at risk of malnutrition, present gastrointestinal comorbidities, and require nutritional support.
Use of Patient-Reported Outcomes Measures in Rheumatoid Arthritis patients in Spain and Barriers to implementation: A Delphi study
This study examined the use and barriers of Patient Reported Outcomes Measures (PROMs) in rheumatoid arthritis (RA) patients in Spain. Although most rheumatologists recognise the importance of PROMs for shared decision-making, only a few incorporate them in routine care, primarily using pain, fatigue, and physical function measures. The main barriers include limited consultation time and […]
Is Less Truly More? Reassessing Safety Analysis for HIV Patients Switching from Triple to Double Regimens with Integrase Inhibitors: A Systematic Review and Meta-Analysis
This study aimed to determine if there are benefits of treatment simplification in terms of safety and tolerability to help in the decision-making in routine clinical practice and to provide the best therapeutic option for patients. This research outlines that there is still insufficient information to claim that simplifying from 3DR or 4DR to 2DR […]
Survey on first-line therapeutic management of relapsing–remitting multiple sclerosis in clinical practice in Spain
Current therapies for relapsing–remitting multiple sclerosis (RRMS) help reduce morbidity and delay disease progression. However, the available information on factors influencing decision-making regarding first-line treatment remains poorly understood.
Preferences of patients and healthcare professionals on lipid-lowering therapies for ASCVD
To describe the patient and HCP preferences regarding the administration of lipid lowering therapies.