Value contribution of trifluridine/tipiracil with bevacizumab for the treatment of metastatic colorectal cancer in Catalonia using a Multi-Criteria Decision Analysis
This study applied a multi-criteria decision analysis (MCDA) to assess the value of trifluridine/tipiracil plus bevacizumab in metastatic colorectal cancer in Catalonia. The combination demonstrated a positive value contribution versus available alternatives, primarily driven by overall survival, safety and clinical efficacy outcomes.
Impact of chronic nodular prurigo on Quality of Life: A Systematic Review of the Literature
Chronic nodular prurigo (CNPG) is an inflammatory skin disease characterized by intense, persistent pruritus associated with nodular lesions resulting from chronic scratching. This condition has a substantial impact on patients’ health-related quality of life, affecting physical, emotional, and psychosocial well-being. Despite its clinical relevance, CNPG remains underrecognized and underrepresented in the scientific literature. This review […]
Recommendations for Diagnosis and Management of Non-Small-Cell Lung Carcinoma Patients with ex20ins EGFR Mutations: Insights from a Delphi Consensus
Delphi Consensus Recommendations for the Management of Patients with EGFR Exon 20 Insertion-Mutated Non-Small Cell Lung Cancer (NSCLC): Integrating Real-World Clinical Practice Perspectives
Preferences of Patients and Cardiologists regarding Pacemaker characteristics in Spain: A Discrete Choice Experiment
Both patients and cardiologists value MRI compatibility and battery longevity most in pacemakers. Patients also prioritise device size, while cardiologists focus more on safety and technical features of the implant.
A systematic literature review of the epidemiological, diagnostic workup, humanistic and economic burden of Alzheimer’s Disease in Spain
Systematic review of the literature on the burden of Alzheimer’s disease due to dementia in Spain over the past five years.
Well-being in psoriasis: Weighting its components using Best and Worst Scalling methodology
Psoriasis is a multifactorial condition where different factors, such as stress or visible lesions, can significantly impact patients’ health-related quality of life (HRQoL). While HRQoL involves the patient’s health status, the concept of well-being encompasses a more comprehensive and subjective view, integrating social, emotional and physical dimensions along with their respective components. This provides a […]
Defining well-being in psoriasis: A Delphi consensus among healthcare professionals and patients
Psoriasis is a chronic skin disease that negatively impacts on patient’s life. A holistic approach integrating well-being assessment could improve disease management. Since a consensus definition of well-being in psoriasis is not available, we aim to achieve a multidisciplinary consensus on well-being definition and its components.
Barriers and Strategies to Optimize the Use of Glucagon‑Like Peptide 1 Receptor Agonists in People with Type 2 Diabetes and High Cardiovascular Risk or Established Cardiovascular Disease: A Delphi Consensus in Spain
A Delphi consensus study conducted in Spain to identify barriers and strategies related to the optimal use of GLP-1 receptor agonists in people with type 2 diabetes and high cardiovascular risk or established cardiovascular disease. The study involved endocrinologists, cardiologists, internists and primary care physicians. The main barriers identified were therapeutic inertia, lack of a […]
Cost-effectiveness Analysis of Maternal Immunization with RSVpreF Vaccine for the Prevention of Respiratory Syncytial Virus Among Infants in Spain
Economic evaluation conducted from the perspective of the Spanish National Health System to assess the cost-effectiveness of maternal immunisation with the bivalent RSVpreF vaccine compared with no intervention for preventing respiratory syncytial virus (RSV) infection in infants. Using a hypothetical cohort model and a Markov-type process, the study estimated clinical outcomes, costs and QALYs. Results […]
Eficiencia de las combinaciones a dosis fija de estatina y ezetimiba en el tratamiento de la hipercolesterolemia
The primary objective of this study was to estimate the clinical and economic benefits derived from increasing the use of fixed-dose combinations of high-intensity statins and ezetimibe in the treatment of hypercholesterolemia in patients at high or very high risk of CV events, from the perspective of the Spanish National Health System (SNS).