Development and testing of a mobile app for systematic collection of patient-reported outcomes (PROs) in patients with hemophilia
Evaluation of a digital solution for the systematic collection of patient-reported outcomes (PROs) in haemophilia. By identifying outcomes relevant to patients and healthcare professionals, the project led to the development and acceptability assessment of MyHemoPRO, a mobile application designed to support routine PRO collection and strengthen patient-centred evidence generation in clinical practice.
Standardized Recommendations for the Implementation of Enhanced Recovery Protocols in Thoracic Surgery in Spain: A Delphi Consensus Study
Despite advancements in minimally invasive techniques, lung resection surgery for lung cancer still carries a significant risk of complications. Enhanced recovery after surgery (ERAS) protocols offer strategies to improve outcomes, yet their adoption is still inconsistent. This study aims to develop a series of evidence-based recommendations for ERAS strategies, incorporating insights from thoracic surgeons, anaesthetists, […]
Resource use and cost associated with cardiovascular, renal, bone and neuropsychiatric comorbidities in people with HIV in Spain
Study measuring the cost associated with comorbidities in people living with HIV during the 2024–2034 period, based on national prevalence data and different assumptions regarding ART (antiretroviral therapy) regimens.
Value contribution of trifluridine/tipiracil with bevacizumab for the treatment of metastatic colorectal cancer in Catalonia using a Multi-Criteria Decision Analysis
Value assessment in metastatic colorectal cancer is becoming increasingly complex due to multiple treatment options and competing decision criteria. This study applies a multicriteria decision analysis (MCDA) framework to capture value beyond traditional endpoints, integrating clinical, economic and patient-reported outcomes. Findings indicate that trifluridine/tipiracil plus bevacizumab delivers a positive overall value contribution compared to available […]
Clinical experience and satisfaction in patients with advanced breast cancer participating in the abemaciclib patient support program in Spain
A real-world study evaluating the impact of a patient support program on managing abemaciclib-related diarrhea in HR+/HER2− metastatic breast cancer. The program improved adherence, patient satisfaction, and quality of life, with no treatment discontinuations.
Human, economic, and social impact of lysosomal storage diseases
Background: Lysosomal storage disorders (LSDs) are a group of rare metabolic conditions caused by enzyme deficiencies, leading to the accumulation of macromolecules within lysosomes. These disorders significantly impact patients’ quality of life (QoL) and impose substantial financial burdens on families and healthcare systems. This study aimed to evaluate the daily life impact and economic burden […]
Real-World Use of ixekizumab for Axial Spondyloarthritis Treatment in Spain (ESPADA Study)
Real-world study evaluating the use of ixekizumab in patients with axial spondyloarthritis in Spain. The study describes treatment patterns and effectiveness in routine clinical practice, reflecting real-world patient management.
Cost-Effectiveness Analysis of Universal Hypothyroidism Screening in the General Population Aged 30 to 65 Years in Spain
Cost-Effectiveness Analysis of Universal Hypothyroidism Screening in the General Population Aged 30 to 65 Years in Spain
Impact of therapeutic inertia in lipid-lowering therapy in patients at very high cardiovascular risk
A high number of patients do not achieve the therapeutic goals set by clinical practice guidelines, despite the therapeutic alternatives that currently exist in lipid-lowering treatment (LLT). This study aimed to estimate the proportion of patients who have recently suffered an acute coronary syndrome (ACS) who do not meet the therapeutic goal with LLT and […]
Usability and validity of a mobile health app for people living with HIV to prepare for the next physician’s visit
Evaluation of the mHealth app PTC as an alternative to PROs in people living with HIV showed high usability, satisfaction, and usefulness. PTC correlated well with validated PROs and enables assessment of quality of life, symptoms, and emotional well-being with lower burden.